I don't usually read manga, but something about the humor in the Me and My Brothers Series, by Hari Tokeino, caught my attention.
The story revolves around a 14 year old girl and her four half brothers. She was raised by her grandma because her parents died when she was young. But then her grandma passed away too, so the four brothers she never met get the task of coming to live with her and raise her.
The story contains some drama, as any family story does, but it also has its fair share of funny situations that are bound to arise in this type of situation.
If you want a cute, funny read, I suggest checking this series out.